Journal of Diabetes Research

Review Article

A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications

Table 1

Genetic markers. Collection of significant genetic markers, listed alphabetically.
Nearest gene(s)VariantEthnicityDiabetes typeAssay typePotential value of biomarkerReferences
18qD18S1364African AmericanT2DLinkage analysisDiagnostic[11]
18q22.3-23D18S43/D18S50TurkishT2DLinkage analysisDiagnostic[12]
18q22.3-23D18S43/D18S50Pima IndiansT2DLinkage analysisDiagnostic[12]
7pD7S3051African AmericanT2DLinkage analysisDiagnostic[11]
AGTR1rs12695897African AmericanT2DCandidate based genotypingDiagnostic[13]
APOL3rs16996381African AmericanT2DGWASDiagnostic[14]
AUHrs773506African AmericanT2DGWASDiagnostic[14]
C12orf66/TMEM5rs11175885African AmericanT2DGWASDiagnostic[14]
C6orf167rs3822908African AmericanT2DGWASDiagnostic[14]
C6orf191/ARHGAP18rs208865African AmericanT2DGWASDiagnostic[14]
CHN2rs2057737African AmericanT2DCandidate based genotypingDiagnostic[13]
CHN2rs3729621African AmericanT2DCandidate based genotypingDiagnostic[13]
CHN2rs3793313African AmericanT2DCandidate based genotypingDiagnostic[13]
CNDP1D18S880EuropeanT1D/T2DCandidate based genotypingDiagnostic[15]
CNDP1D18S880MultiethnicT2DMeta-analysisDiagnostic[16]
CNDP1rs4892249African AmericanT2DCandidate based genotypingDiagnostic[13]
CNDP1rs6566815African AmericanT2DCandidate based genotypingDiagnostic[13]
CNDP1D18S880CaucasianT2DMeta-analysisDiagnostic[17]
ELMO1rs741301AsianT2DMeta-analysisDiagnostic[16]
ELMO1rs11769038CaucasianT1DGWASDiagnostic[18]
ELMO1rs1882080CaucasianT1DGWASDiagnostic[18]
ELMO1rs2041801CaucasianT1DGWASDiagnostic[18]
ELMO1rs7785934CaucasianT1DGWASDiagnostic[18]
ELMO1Intron 18 + 9170 (A/G)JapaneseT2DGWASDiagnostic[19]
FRMD3rs1535753African AmericanT2DGWASDiagnostic[20]
FRMD3rs2378658African AmericanT2DGWASDiagnostic[20]
FRMD3rs942278African AmericanT2DGWASDiagnostic[20]
FRMD3rs942280African AmericanT2DGWASDiagnostic[20]
FRMD3rs942283African AmericanT2DGWASDiagnostic[20]
FRMD3rs1888747EuropeanT2DCandidate based genotypingDiagnostic[21]
GRIK2rs7760831African AmericanT2DGWASDiagnostic[14]
GRIP1/CAND1rs11176482African AmericanT2DGWASDiagnostic[14]
GRIP1/CAND1rs2904532African AmericanT2DGWASDiagnostic[14]
LIMK2rs2106294African AmericanT2DGWASDiagnostic[14]
LIMK2rs4820043African AmericanT2DGWASDiagnostic[14]
MSRB3/HMGA2rs2358944African AmericanT2DGWASDiagnostic[14]
MYH9rs735853African AmericanT2DGWASDiagnostic[14]
NAV3rs12302041African AmericanT2DGWASDiagnostic[14]
NDrs1978243African AmericanT2DGWASDiagnostic[14]
NDrs4260465African AmericanT2DGWASDiagnostic[14]
NDrs7697691African AmericanT2DGWASDiagnostic[14]
OR2L13rs10888287African AmericanT2DGWASDiagnostic[14]
PVT1rs2648875Pima IndiansT2DGWASDiagnostic[22]
PVT1rs13447075EuropeanT1DCandidate based genotypingDiagnostic[23]
RNF185rs1034589African AmericanT2DGWASDiagnostic[14]
RPS12rs7769051African AmericanT2DGWASDiagnostic[14]
RPS12rs9493454African AmericanT2DGWASDiagnostic[14]
SASH1rs6930576African AmericanT2DGWASDiagnostic[14]
SFI1rs5749286African AmericanT2DGWASDiagnostic[14]
SLC10A7/LSM6rs891382African AmericanT2DGWASDiagnostic[14]
TPM1rs6494387African AmericanT2DGWASDiagnostic[14]
UNC5Crs11730446African AmericanT2DGWASDiagnostic[14]