Impact of the Type of Continuous Insulin Administration on Metabolism in a Diabetic Rat Model

Figure 2

Plasma levels of human insulin at 5 h (a) and 22 h (b) after insulin administration. For both control nondiabetic (CTL ND) and diabetic rats which received no insulin treatment, human insulin was undetectable at or  h. At  h, both injection and pump rats presented a high level of detectable insulin, but at 22 h thereafter, only the pump group levels continued to increase while the injection group levels did not. CTL ND and diabetic groups are different from injection and pump groups at all times since 7 days () (a); pump group is different from all other groups at all times since 7 days () (b). .

(a)

(b)