Modulation Effect of Peroxisome Proliferator-Activated Receptor Agonists on Lipid Droplet Proteins in Liver

Figure 1

PPAR agonists’ treatment improved glucose tolerance and insulin sensitivity in high-fat diet-induced obese mice. Mice were fed with either a normal chow diet (Chow) or a high-fat diet (HF) for 20 weeks and treated with either pioglitazone or fenofibrate. (a) Intraperitoneal glucose tolerance test (GTT), (b) insulin tolerance test (ITT), (c) AUC of GTT, and (d) AUC of ITT. HF-P: mice fed a high-fat diet and treated with pioglitazone; HF-F: mice fed a high-fat diet and treated with fenofibrate. a: versus Chow and b: versus HF; ; .

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