Research Article

Heart Rate Variability as Early Biomarker for the Evaluation of Diabetes Mellitus Progress

Table 1

Characterization of diabetes in cDM-model.

Metabolic parameters
CT ()cDM-model ()

Water intake (mL)6 ± 0.460 ± 7
Food intake (g)5 ± 0.28 ± 0.7
Feces excreted (g)1.8 ± 0.25 ± 0.5
Urine excreted (mL)0.4 ± 0.140 ± 6

Clinical biochemistry values
Serum electrolytesCT ()cDM-model ()

Sodium (mmol/L)149 ± 1 154 ± 4
Potassium (mmol/L)9 ± 0.5 11 ± 0.4
Chloride (mmol/L)115 ± 2 115 ± 4
Calcium (mg/dL)9.4 ± 0.2 9.5 ± 0.6

Urine test strip
CT ()cDM-model ()

KetonesNegative (100%)0.1 ± 0.06 (20%)
Glucose (mg/dL)Negative (100%)722.5 ± 149.7 (100%)
Protein (mg/dL)Traces (47%)24 ± 6 (85%)
Blood (ery/µL)Negative (100%)16.1 ± 4.54 (50%)
pH6.40 ± 0.14 (100%)6.05 ± 0.2 (100%)
NitritesPositive (9%)Positive (43%)
Leukocytes (leuk/µL)Negative (100%)30.83 ± 8 (30%)
Specific gravity1.02 ± 0.001 (100%)1.01 ± 0.0006 (100%)
UrobilinogenNegative (100%)Negative (100%)
BilirubinNegative (100%)Negative (100%)

The data obtained on metabolic cage and urine of 24 hours. The values are described as mean ± SEM. Student’s -test  .