Plasma C1q/TNF-Related Protein-9 Levels Are Associated with Atherosclerosis in Patients with Type 2 Diabetes without Renal Dysfunction

Table 2

Factors independently associated with carotid atherosclerosis in subgroups with and without CKD.

	Max-IMT		Mean-IMT
	Non-CKD	CKD	Non-CKD	CKD
Age (years)		0.101
Sex (male = 1, female = 0)	0.046	0.015	0.111	0.114
BMI (kg/m^2)	−0.051	−0.060	−0.077
Systolic BP (mmHg)	0.064	0.110	0.061	0.163
eGFR (mL/min/1.73 m^2)	0.039	0.097	0.019	0.121
HbA1c (%)	0.025	−0.019	0.014	0.003
Triglycerides (mg/dL)	−0.092	0.054	−0.047	0.066
HDL-cholesterol (mg/dL)	−0.070	−0.118	−0.042	−0.122
LDL-cholesterol (mg/dL)	0.112	0.001		0.039
ARB/ACEI (yes = 1)	−0.080	0.027	−0.012	−0.074
Statin (yes = 1)	−0.002		0.025	−0.066
Smoker (yes = 1)	0.021	0.004	0.036	0.017
Adiponectin (μg/mL)	−0.109	0.013	−0.073	0.004
CTRP9 (μg/mL)		0.097		0.078
		0.087

The table shows the results of four multiple regression analyses in subjects with type 2 diabetes with CKD and those without CKD. The dependent variables were max-IMT (the left two columns) and mean-IMT (the right two columns). Values are standardized regression coefficients (). , coefficient of determination; ,  ; ,  . BMI, body mass index; BP, blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ARB/ACEI, prevalence of subjects treated with angiotensin II receptor antagonists or ACE inhibitors; statin, prevalence of subjects treated with stains; smoker, prevalence of current and past smokers; CTRP, C1q/TNF-related protein.