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Journal of Diabetes Research
Volume 2016, Article ID 9073037, 9 pages
Research Article

Advanced Glycation End Products Impair Glucose-Stimulated Insulin Secretion of a Pancreatic β-Cell Line INS-1-3 by Disturbance of Microtubule Cytoskeleton via p38/MAPK Activation

Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China

Received 26 April 2016; Accepted 30 June 2016

Academic Editor: Ronald G. Tilton

Copyright © 2016 Jia You et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Fig S1. p38/MAPK inhibitor SB203580 cannot rescue AGEs-impaired GSIS.

  1. Supplementary Figure