A Novel Wistar Rat Model of Obesity-Related Nonalcoholic Fatty Liver Disease Induced by Sucrose-Rich Diet

Table 3

Comparison of hormonal levels and enzyme activity between experimental and control groups.

Time (weeks)	Groups		P value
	Experimental	Control
Insulin (µL)^‡
5	7.6 (3.8–11.1)	1.6 (1.5–2.1)	0.005
10	4.7 (3.4–8.2)	1.7 (1.6–3.1)	0.013
20	0.9 (0.6–1.1)	0.3 (0.3–0.4)	0.008
30	0.4 (0.3–0.8)	0.2 (0.2–0.4)	0.043
Leptin (µL)^‡
5	14.3 (11.7–18.9)	6.6 (5.8–7.6)	0.001
10	13.7 (9.6–20.9)	4.4 (3.6–4.8)	0.005
20	18.2 (10.3–25.9)	5.1 (3.3–8.1)	0.021
30	24.7 (13.1–37.0)	2.6 (1.8–5.7)	<0.001
Superoxide dismutase (U/mg protein)^†
5	1.5 (±0.1)	1.6 (±0.03)	0.090
10	1.6 (±0.02)	1.6 (±0.1)	1.000
20	1.6 (±0.1)	1.5 (±0.1)	0.288
30	0.9 (±0.3)	1.4 (±0.1)	<0.001
Catalase
(mmol of H2O2 decomposed/minute/milligram of protein)^†
5	15.8 (±2.4)	15.9 (±2.7)	0.948
10	14.3 (±3.1)	15.9 (±2.7)	0.411
20	11.8 (±1.4)	15.1 (±2.9)	0.037
30	14.6 (±1.9)	16.7 (±3.5)	0.111

-test for normally distributed and Mann-Whitney test for nonnormally distributed variables; ^†mean ± standard deviation; ^‡median (interquartile range).