N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats
Table 1
General parameters during feeding period.
Groups
Food intake (g/kg/day)
Water intake (mL/kg/day)
Weight (g)
Blood glucose (mmol/L)
1–4 weeks
5–8 weeks
1–4 weeks
5–8 weeks
1–4 weeks
5–8 weeks
1–4 weeks
5–8 weeks
Sham
73 ± 4.9
69.1 ± 3.5
149.6 ± 5.4
165.6 ± 9.7
361.3 ± 13.0
433.0 ± 18.0
5.5 ± 0.3
5.3 ± 0.4
Control
76.5 ± 3.5
70.1 ± 1.5
154.5 ± 2.1
156.3 ± 0.6
360.5 ± 11.6
432.0 ± 11.2
5.4 ± 0.4
5.9 ± 0.3
I + S
67.2 ± 4.6
66.6 ± 2.2
155.2 ± 3.2
150.3 ± 3.0
370.0 ± 13.7
274.3 ± 9.2
5.5 ± 0.3
5.7 ± 0.2
T + I
177.9 ± 24.1
187.3 ± 2.9
887.9 ± 158.3
1118.8 ± 12.2
271.3 ± 10.4
238.8 ± 0.9
28.0 ± 2.0
29.5 ± 1.1
T + I + S
180.8 ± 19.4
206.3 ± 1.6
927.8 ± 170.5
1224.0 ± 10.5
274.3 ± 9.2
271.3 ± 10.4
26.9 ± 2.1
26.1 ± 1.5
T + I + N
188.8 ± 24.2
170.6 ± 6.5
1072.5 ± 78.2
614.1 ± 130.8
254.8 ± 15.7
253.5 ± 4.6
29.1 ± 1.2
27.4 ± 2.5
T + I + N + S
192.5 ± 8.0
154.5 ± 16.5
1110.9 ± 52.5
677.0 ± 105.2
253.3 ± 10.3
269.5 ± 13.8
26.3 ± 2.0
27.5 ± 1.7
Data was expressed as mean ± SEM (); I, T, S, and N, respectively, stand for ischemia-reperfusion (I), Type 1 diabetes (T), sevoflurane (S), and N-Acetylcysteine (N); control: ischemia-reperfusion untreated group. compared with control group; and compared with T + I group.
