Clinical Study

Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research)

Table 2

Indices of insulin sensitivity and cell function derived from OGTT measurements of glucose and insulin.

IndexFormulaReference

HOMA-IR[FPG (mmol/L) FINS (mU/L)]/22.5[10, 11]
Insulin/glucose ratioFINS (mU/L)/FPG (mmol/L)[12, 13]
QUICKI1/[LogFINS (mU/L) + LogFPG (mg/dL)][14]
Matsuda index10000/[FPG (mg/dL) × FINS (mU/L) × (mean glucose × mean insulin)][15]
Gutt index{75000 + [GLU0 (mg/dL) − GLU120] × 0.19 × body weight (kg)}/{120 × log [mean insulin (mU/L)] × mean glucose}[16]
HOMA-20 × FINS (mU/L)/[FPG (mmol/L) − 3.5]%[10, 11]
Disposition indexHOMA-/HOMA-IR[17]
Insulinogenic index[INS120 (mU/L) − INS0]/[GLU120 (mmol/L) − GLU0][18]