The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands
Table 1
General characteristics of the study subjects.
South Asians ()
Europeans ()
noMetS/noT2D
MetS/noT2D
MetS/T2D
noMetS/noT2D
MetS/noT2D
MetS/T2D
12
14
18
31
12
11
Male/female
6/6
9/5
10/8
9/22
5/7
6/5
Age (yrs)
33.9 ± 8.0
48.2 ± 10.1
51.4 ± 10.4
39.6 ± 10.2
40.3 ± 10.2
61.8 ± 8.7
Height (m)
1.67 ± 0.12
1.68 ± 0.12
1.63 ± 0.08
1.75 ± 0.10
1.78 ± 0.08
1.77 ± 0.07
Weight (kg)
74.1 ± 16.3
78.8 ± 9.6
76.3 ± 12.4
77.8 ± 12.2
103.5 ± 28.7
98.3 ± 11.8
Body mass index (kg/m2)
26.3 ± 3.3
28 ± 2.7
28.7 ± 4.1
25.4 ± 3.1
32.6 ± 8.2
31.4 ± 4.3
Waist (cm)
93 ± 12
98 ± 9
97 ± 7
88 ± 12
110 ± 19
110 ± 13
Hip (cm)
105 ± 7
104 ± 4
103 ± 8
106 ± 8
120 ± 16
116 ± 8
Waist-to-hip ratio
0.89 ± 0.08
0.94 ± 0.07
0.95 ± 0.08
0.83 ± 0.09
0.92 ± 0.08
0.94 ± 0.07
Systolic blood pressure (mmHg)
114 ± 11
130 ± 16
136 ± 15
120 ± 12
137 ± 14
137 ± 14
Diastolic blood pressure (mmHg)
76 ± 9
83 ± 12
82 ± 9
74 ± 8
84 ± 9
84 ± 11
Total cholesterol (mmol/L)
4.7 ± 0.7
5 ± 0.9
4.6 ± 1.2
4.8 ± 1
4.9 ± 0.9
4.5 ± 1.1
Triglycerides (mmol/L)
0.97 ± 0.37
1.43 ± 0.65
1.55 ± 0.65
0.97 ± 0.36
1.39 ± 0.77
1.38 ± 0.55
HDL (mmol/L)
1.19 ± 0.37
1.01 ± 0.21
1.05 ± 0.22
1.47 ± 0.40
1.11 ± 0.19
1.17 ± 0.26
LDL (mmol/L)
3.02 ± 0.63
3.30 ± 0.76
2.80 ± 1.08
2.77 ± 0.93
3.01 ± 0.80
2.55 ± 0.90
Ratio HDL-cholesterol
4.2 ± 1.3
5.2 ± 1.4
4.4 ± 1.2
3.5 ± 1.1
4.5 ± 1.2
3.9 ± 0.9
Fasting plasma glucose (mmol/L)
5.3 ± 0.3
5.8 ± 0.5
7.4 ± 1.5
5.3 ± 0.5
5.7 ± 0.5
8.1 ± 1.1
OGTT (mmol/L)
5.5 ± 1.7
6.8 ± 1.2
13.8 ± 5.2
5.7 ± 1.5
6.7 ± 1.8
13.9 ± 2.8
Insulin (pmol/L)
53.5 ± 46.8
73.8 ± 49.2
58.3 ± 38.4
35.8 ± 29
73.7 ± 35.6
78.5 ± 72.2
HDL: high-density lipoprotein; LDL: low-density lipoprotein; OGTT: oral glucose tolerance test (2 hours); MetS: metabolic syndrome; T2D: type 2 diabetes mellitus. indicates statistically significant differences between the noMetS/noT2D and the other 2 subgroups within Europeans; indicates statistically significant differences between the MetS/noT2D and the Met/T2D subgroup within Europeans; indicates statistically significant differences between noMetS/noT2D and the other 2 subgroups within South Asians; indicates statistically significant differences between MetS/noT2D and the Met/T2D subgroup within South Asians.
