Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E₂ and F₂α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Diabetes

Table 3

Malformations present in the two diabetic groups (vehicle- and LA-treated group).

	Vehicle-treated diabetic (V-TD)		LA-treated diabetic (LA-TD)
	Nonmalformed	Malformed	Nonmalformed	Malformed
Fetal number	16	32 (66.66%)	34	25 (42.37%)
Fetal body weight (mg)
Placental weight (mg)
Membrane weight (mg)
CRL (mm)
Short mandible		19 (39.58%)		6 (10.17%)
Open neural tube		15 (31.25%)		8 (13.56%)
Malrotation		6 (12.5%)		3 (5.09%)
Short tail		1 (2.08%)		0 (0.00%)

higher () compared with malformed LA-TD.
higher () compared with V-TD rats (nonmalformed and malformed).
to increase more than malformed V-TD ().
There are no significant relationships between placental and membrane body weights of any groups.
The difference in the mean values of the two groups is statistically significantly different using Shapiro-Wilk and Mann-Whitney one way analysis of variance rank sum test.