Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E₂ and F₂α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Diabetes

Table 5

COX activity in fetuses (U/mg of protein).

Groups	Total COX		COX-1		COX-2
Vehicle-treated control (V-TC) ()
LA-treated control (LA-TC) ()
	Nonmalformed		Nonmalformed	Malformed	Nonmalformed
Vehicle-treated diabetic (V-TD) ()
LA-treated diabetic (LA-TD) ()

lower () compared with fetuses from V-TC, LA-TC, and nonmalformed groups of both groups of diabetic rats.