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Journal of Diabetes Research
Volume 2016, Article ID 9570424, 8 pages
Research Article

Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control

1Copenhagen Diabetes Research Center (CPH-DIRECT), Department of Pediatrics E, University Hospital Herlev, 2730 Herlev, Denmark
2Novo Nordisk A/S, 2760 Måløv, Denmark
3DECCP, Clinique Pédiatrique, CH de Luxembourg, 4 rue Barblé, 1210 Luxembourg, Luxembourg

Received 8 October 2015; Accepted 4 November 2015

Academic Editor: Marco Songini

Copyright © 2016 Caroline A. Brorsson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table 1: The risk allele distribution of the 11 T1D candidate genes.

Supplementary Table 2.: Variance explained by regression models for HbA1c and IDAA1c with and without genetic risk score (GRS).

  1. Supplementary Material