Journal of Diabetes Research / 2016 / Article / Tab 1

Research Article

Effect of Endomorphins on HUVECs Treated by ox-LDL and Its Related Mechanisms

Table 1

The positive granule area, average light density, and integrated light density of p-JNK in HUVECs induced by ox-LDL increased for 48 h and prevented by EM1/EM2 by image-pro plus. Data is expressed as mean ± SD. ⁢ versus control. versus ox-LDL.

GroupPositive granule area (m2)Average light density (PU)Integrated light density (PU)

Normal culture group470 ± 270.28 ± 0.074.56 ± 0.38
Cultured in ox-LDL group4753 ± 760.84 ± 0.0531.44 ± 0.74
EM1 (10 nmol/L) group3242 ± 640.79 ± 0.0526.03 ± 0.67
EM1 (100 nmol/L) group2036 ± 69#0.74 ± 0.06#19.87 ± 0.51#
EM1 (1000 nmol/L) group1228 ± 87#0.68 ± 0.06#13.11 ± 0.63#
EM1 (10000 nmol/L) group1143 ± 77#0.56 ± 0.08#11.89 ± 0.57#
10.0 M SP600125+EM1 (10000 nmol/L) 873 ± 68#0.41 ± 0.07#8.23 ± 0.41#
EM2 (10 nmol/L) group3223 ± 700.83 ± 0.0525.74 ± 0.54
EM2 (100 nmol/L) group1916 ± 65#0.72 ± 0.03#18.94 ± 0.47#
EM2 (1000 nmol/L) group1079 ± 47#0.62 ± 0.06#12.03 ± 0.51#
EM2 (10000 nmol/L) group957 ± 59#0.53 ± 0.06#10.81 ± 0.43#
10.0 M SP600125+EM2 (10000 nmol/L) 769 ± 46#0.38 ± 0.05#7.56 ± 0.39#

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