Effect of Endomorphins on HUVECs Treated by ox-LDL and Its Related Mechanisms

Table 1

The positive granule area, average light density, and integrated light density of p-JNK in HUVECs induced by ox-LDL increased for 48 h and prevented by EM1/EM2 by image-pro plus. Data is expressed as mean ± SD. ⁢ versus control. versus ox-LDL.

Group	Positive granule area (m^2)	Average light density (PU)	Integrated light density (PU)
Normal culture group	470 ± 27	0.28 ± 0.07	4.56 ± 0.38
Cultured in ox-LDL group	4753 ± 76	0.84 ± 0.05	31.44 ± 0.74
EM1 (10 nmol/L) group	3242 ± 64	0.79 ± 0.05	26.03 ± 0.67
EM1 (100 nmol/L) group	2036 ± 69^#	0.74 ± 0.06^#	19.87 ± 0.51^#
EM1 (1000 nmol/L) group	1228 ± 87^#	0.68 ± 0.06^#	13.11 ± 0.63^#
EM1 (10000 nmol/L) group	1143 ± 77^#	0.56 ± 0.08^#	11.89 ± 0.57^#
10.0 M SP600125+EM1 (10000 nmol/L)	873 ± 68^#	0.41 ± 0.07^#	8.23 ± 0.41^#
EM2 (10 nmol/L) group	3223 ± 70	0.83 ± 0.05	25.74 ± 0.54
EM2 (100 nmol/L) group	1916 ± 65^#	0.72 ± 0.03^#	18.94 ± 0.47^#
EM2 (1000 nmol/L) group	1079 ± 47^#	0.62 ± 0.06^#	12.03 ± 0.51^#
EM2 (10000 nmol/L) group	957 ± 59^#	0.53 ± 0.06^#	10.81 ± 0.43^#
10.0 M SP600125+EM2 (10000 nmol/L)	769 ± 46^#	0.38 ± 0.05^#	7.56 ± 0.39^#