Irisin: A Potential Link between Physical Exercise and Metabolism—An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People
Table 1
Univariate association between plasma irisin level and demographic, anthropometric, and biochemical parameters in differently trained individuals: (a) elite + subelite group, (b) recreational group, and (c) sedentary group.
(a) Elite and subelite
Age
−0.16
0.336
BMI
−0.11
0.512
Fasting glucose
−0.477
0.003
Fasting insulin
−0.058
0.730
Total cholesterol
−0.329
0.047
Triglycerides
−0.441
0.006
NEFA
−0.545
0.001
HbA1c
−0.206
0.221
HOMA-IR
−0.065
0.698
Irisin/HOMA-IR
0.633
<0.0001
(b) Recreational
Age
−0.667
0.967
BMI
0.268
0.090
Fasting glucose
−0.306
0.006
Fasting insulin
0.142
0.399
Total cholesterol
0.004
0.792
Triglycerides
−0.137
0.411
NEFA
0.075
0.66
HbA1c
−0.139
0.413
HOMA-IR
0.203
0.203
Irisin/HOMA-IR
0.603
<0.0001
(c) Sedentary
Age
−0.278
0.436
BMI
−0.217
0.548
Fasting glucose
0.103
0.777
Fasting insulin
0.395
0.333
Total cholesterol
0.09
0.803
Triglycerides
0.4001
0.251
NEFA
−0.134
0.752
HbA1c
−0.601
0.087
HOMA-IR
0.288
0.419
Irisin/HOMA-IR
0.833
0.003
Associations between variables were explored using Pearson or Spearman correlation coefficients, as appropriate. Pearson correlation; Spearman correlation. BMI, body mass index; NEFA, free fatty acids; HbA1c, glycated hemoglobin; HOMA-IR, HomeOstasis Model Assessment for estimating insulin resistance.
