Research Article

Peripheral and Autonomic Neuropathy in South Asians and White Caucasians with Type 2 Diabetes Mellitus: Possible Explanations for Epidemiological Differences

Table 2

Ethnic differences in components of the MNSI and monofilament perception. Data are presented as % of abnormal test/response in the particular ethnic groups. MNSIe: the examination component of MNSI. MNSIq: the questionnaire component of MNSI. questions are not scored as part of the MNSIq. and < 0.0033 were considered significant for differences in the components of MNSIe and MNSIq, respectively, following the Bonferroni correction. Statistical analysis in this table represents univariate analysis with no adjustments.

South Asian
()
White Caucasian
()
values

MNSIe
 Inspection51.663.30.054
 Ulcers1.64.30.195
 Ankle reflexes35.756.10.001
 Vibration32.554.7<0.001

10 g monofilament23.843.90.001

MNSIq
 Are your legs and/or feet numb?46.841.40.376
 Do you ever have any burning pain in your legs and/or feet?55.643.60.051
 Are your feet too sensitive to touch?24.626.40.733
 Do you get muscle cramps in your legs and/or feet62.770.70.165
 Do you ever have any prickling feelings in your legs or feet?59.544.30.013
 Does it hurt when the bed covers touch your skin?14.311.40.486
 When you get into the tub or shower, are you able to tell the hot water from the cold water?7.910.00.558
 Have you ever had an open sore on your foot?11.125.70.002
 Has your doctor ever told you that you have diabetic neuropathy?20.627.10.215
 Do you feel weak all over most of the time53.233.60.001
 Are your symptoms worse at night?43.736.40.230
 Do your legs hurt when you walk?59.560.70.843
 Are you able to sense your feet when you walk?8.717.10.043
 Is the skin on your feet so dry that it cracks open?38.946.40.215
 Have you ever had an amputation?2.48.60.029