Research Article
Relationships between Composition of Major Fatty Acids and Fat Distribution and Insulin Resistance in Japanese
Table 3
Stepwise regression analysis of relationships between dependent variables and the most significant independent FFA variables.
| | Dependent variable | Contributory cause | Correlation coefficient | value | value |
| | BMI (kg/m2) | Palmitic acid | | 14.707 | <0.0001 | | sBP (mmHg) | Linoleic acid | | 5.732 | 0.0184 | | dBP (mmHg) | — | — | — | — | | Biomarkers | | | | | | 0 min glu (mg/dL) | Linoleic acid | | 9.383 | <0.0001 | | 120 min glu (mg/dL) | Linoleic acid | | 14.041 | <0.0001 | | 0 min IRI (μU/mL) | Myristic acid | | 14.014 | <0.0001 | | 120 min IRI (μU/mL) | Palmitoleic acid | | 12.237 | 0.0006 | | HbA1c (N) (%) | Linoleic acid | | 6.165 | 0.0146 | | HOMA-IR | Myristic acid | | 13.792 | <0.0001 | | I.I. | — | — | — | — | | TC (mg/dL) | Linolenic acid | | 5.554 | 0.0216 | | TG (mg/dL) | Oleic acid | | 26.853 | <0.0001 | | HDL-C (mg/dL) | Oleic acid | | 18.722 | <0.0001 | | LDL-C (mg/dL) | Behenic acid | | 6.584 | 0.0134 | | AST (IU/L) | Myristic acid | | 8.467 | 0.0044 | | ALT (IU/L) | Palmitic acid | | 9.86 | 0.0022 | | Cre (mg/dL) | Gamma linolenic acid | | 6.022 | 0.0337 | | UA (mg/dL) | Eicosenoic acid | | 6.002 | 0.0162 | | HMW-ADPN (μg/mL) () | Linoleic acid | | 12.917 | 0.0108 | | Leptin (ng/mL) () | Lauric acid | | 6.157 | 0.0159 | | CT scan | | | | | | V-fat (cm2) | Linoleic acid | | 17.73 | <0.0001 | | S-fat (cm2) | Dihomo-γ-linolenic acid | | 9.221 | 0.0002 |
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BMI: body mass index; sBP: systolic blood pressure; dBP: diastolic blood pressure; 0 min glu: 0 min glucose; 120 min glu: 120 min glucose; 0 min IRI: 0 min immunoreactive insulin; 120 min IRI: 120 min-immunoreactive insulin; HbA1c: hemoglobin A1c; HOMA-IR: homeostasis model assessment insulin resistance index; I.I.: insulinogenic index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; AST: aspartate aminotransferase; ALT: alanine aminotransferase; Cre: creatinine; UA: uric acid; HMW-ADPN: high molecular weight adiponectin; V-fat: visceral fat area; S-fat: subcutaneous fat area.
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