Table of Contents Author Guidelines Submit a Manuscript
Journal of Diabetes Research
Volume 2017, Article ID 2042980, 8 pages
Research Article

All-Cause Mortality Risk in Australian Women with Impaired Fasting Glucose and Diabetes

1Deakin University, Geelong, VIC 3220, Australia
2Department of Medicine-Western Health, Melbourne Medical School, The University of Melbourne, St Albans, VIC 3010, Australia
3Barwon Health, Geelong, VIC 3220, Australia

Correspondence should be addressed to Lelia L. F. de Abreu; ua.gro.htlaehnowrab@uerbaedl

Received 29 March 2017; Revised 15 May 2017; Accepted 23 May 2017; Published 18 June 2017

Academic Editor: Mark A. Yorek

Copyright © 2017 Lelia L. F. Abreu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aims. Impaired fasting glucose (IFG) and diabetes are increasing in prevalence worldwide and lead to serious health problems. The aim of this longitudinal study was to investigate the association between impaired fasting glucose or diabetes and mortality over a 10-year period in Australian women. Methods. This study included 1167 women (ages 20–94 yr) enrolled in the Geelong Osteoporosis Study. Hazard ratios for all-cause mortality in diabetes, IFG, and normoglycaemia were calculated using a Cox proportional hazards model. Results. Women with diabetes were older and had higher measures of adiposity, LDL cholesterol, and triglycerides compared to the IFG and normoglycaemia groups (all ). Mortality rate was greater in women with diabetes compared to both the IFG and normoglycaemia groups (HR 1.8; 95% CI 1.3–2.7). Mortality was not different in women with IFG compared to those with normoglycaemia (HR 1.0; 95% CI 0.7–1.4). Conclusions. This study reports an association between diabetes and all-cause mortality. However, no association was detected between IFG and all-cause mortality. We also showed that mortality in Australian women with diabetes continues to be elevated and women with IFG are a valuable target for prevention of premature mortality associated with diabetes.