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Journal of Diabetes Research
Volume 2017, Article ID 2180819, 9 pages
https://doi.org/10.1155/2017/2180819
Research Article

Expression Profile of Genes Potentially Associated with Adequate Glycemic Control in Patients with Type 2 Diabetes Mellitus

1Department of Diagnosis and Surgery, School of Dentistry, Universidade Estadual Paulista (UNESP), Araraquara, SP, Brazil
2Department of Morphology, School of Dentistry, Universidade Estadual Paulista (UNESP), Araraquara, SP, Brazil
3Postgraduate Program in Sciences of the University of Franca, Franca, SP, Brazil
4Department of Genetics, Faculty of Medicine of Ribeirão Preto and Department of Biology, FFCLRP, University of São Paulo (USP), Ribeirão Preto, SP, Brazil
5Department of Medical Genetics, University of Campinas (UNICAMP), Campinas, SP, Brazil

Correspondence should be addressed to Raquel Mantuaneli Scarel-Caminaga; rb.psenu.raof@leuqar

Received 16 April 2017; Revised 22 May 2017; Accepted 31 May 2017; Published 25 July 2017

Academic Editor: Hiroshi Okamoto

Copyright © 2017 Sâmia Cruz Tfaile Corbi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. M. Zuniga-Gonzalez, C. M. Batista-Gonzalez, B. C. Gomez-Meda et al., “Micronuclei in diabetes: folate supplementation diminishes micronuclei in diabetic patients but not in an animal model,” Mutation Research, vol. 634, no. 1-2, pp. 126–134, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. P. M. Duarte, J. P. Bezerra, T. S. Miranda, M. Feres, L. Chambrone, and L. M. Shaddox, “Local levels of inflammatory mediators in uncontrolled type 2 diabetic subjects with chronic periodontitis,” Journal of Clinical Periodontology, vol. 41, no. 1, pp. 11–18, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. E. Tatsch, G. V. Bochi, S. J. Piva et al., “Association between DNA strand breakage and oxidative, inflammatory and endothelial biomarkers in type 2 diabetes,” Mutation Research, vol. 732, no. 1-2, pp. 16–20, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Kataoka, M. Shao, K. Wolski et al., “Multiple risk factor intervention and progression of coronary atherosclerosis in patients with type 2 diabetes mellitus,” European Journal of Preventive Cardiology, vol. 20, no. 2, pp. 209–217, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. A. D. Mooradian, “Dyslipidemia in type 2 diabetes mellitus,” Nature Clinical Practice Endocrinology & Metabolism, vol. 5, no. 3, pp. 150–159, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Soory, “Inflammatory mechanisms and redox status in periodontal and cardiometabolic diseases: effects of adjunctive nutritional antioxidants and statins,” Infectious Disorders Drug Targets, vol. 12, no. 4, pp. 301–315, 2012. View at Google Scholar
  7. A. M. Iacopino, “Periodontitis and diabetes interrelationships: role of inflammation,” Annals of Periodontology/the American Academy of Periodontology, vol. 6, no. 1, pp. 125–137, 2001. View at Publisher · View at Google Scholar
  8. C. W. Cutler, E. A. Shinedling, M. Nunn et al., “Association between periodontitis and hyperlipidemia: cause or effect?” Journal of Periodontology, vol. 70, no. 12, pp. 1429–1434, 1999. View at Publisher · View at Google Scholar
  9. P. O. Nassar, C. S. Walker, C. S. Salvador, F. A. Felipetti, S. R. Orrico, and C. A. Nassar, “Lipid profile of people with diabetes mellitus type 2 and periodontal disease,” Diabetes Research and Clinical Practice, vol. 96, no. 1, pp. 35–39, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Almeida Abdo, F. R. Cirano, M. Z. Casati et al., “Influence of dyslipidemia and diabetes mellitus on chronic periodontal disease,” Journal of Periodontology, vol. 84, no. 10, pp. 1401–1408, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. A. Pacilli, S. D. Cosmo, V. Trischitta, and S. Bacci, “Role of relationship between HbA1c, fibrinogen and HDL-cholesterol on cardiovascular disease in patients with type 2 diabetes mellitus,” Atherosclerosis, vol. 228, no. 1, pp. 247-248, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. C. W. Cutler, R. L. Machen, R. Jotwani, and A. M. Iacopino, “Heightened gingival inflammation and attachment loss in type 2 diabetics with hyperlipidemia,” Journal of Periodontology, vol. 70, no. 11, pp. 1313–1321, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. F. Ismail-Beigi, T. Craven, M. A. Banerji et al., “Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial,” Lancet, vol. 376, no. 9739, pp. 419–430, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. ACCORD Study Group, ACCORD Eye Study Group, E. Y. Chew et al., “Effects of medical therapies on retinopathy progression in type 2 diabetes,” The New England Journal of Medicine, vol. 363, no. 3, pp. 233–244, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Feng, Y. Liu, L. M. Chu et al., “Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes,” Circulation, vol. 126, no. 11, pp. 73–80, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. F. S. Manoel-Caetano, D. J. Xavier, A. F. Evangelista et al., “Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease,” Gene, vol. 511, no. 2, pp. 151–160, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. P. C. Tsiotra, C. Tsigos, E. Yfanti et al., “Visfatin, TNF-alpha and IL-6 mRNA expression is increased in mononuclear cells from type 2 diabetic women,” Hormone and Metabolic Research = Hormon- und Stoffwechselforschung = Hormones et Metabolisme, vol. 39, no. 10, pp. 758–763, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Gokulakrishnan, K. T. Mohanavalli, F. Monickaraj, V. Mohan, and M. Balasubramanyam, “Subclinical inflammation/oxidation as revealed by altered gene expression profiles in subjects with impaired glucose tolerance and type 2 diabetes patients,” Molecular and Cellular Biochemistry, vol. 324, no. 1-2, pp. 173–181, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. A. de Souza Bastos , D. T. Graves, A. P. d. Melo Loureiro et al., “Diabetes and increased lipid peroxidation are associated with systemic inflammation even in well-controlled patients,” Journal of Diabetes and Its Complications, vol. 30, no. 8, pp. 1593–1599, 2016. View at Publisher · View at Google Scholar · View at Scopus
  20. A. S. Bastos, D. T. Graves, A. P. Loureiro et al., “Lipid peroxidation is associated with the severity of periodontal disease and local inflammatory markers in patients with type 2 diabetes,” The Journal of Clinical Endocrinology and Metabolism, vol. 97, no. 8, pp. 1353–1362, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. S. C. Corbi, A. S. Bastos, S. R. Orrico et al., “Elevated micronucleus frequency in patients with type 2 diabetes, dyslipidemia and periodontitis,” Mutagenesis, vol. 29, no. 6, pp. 433–439, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. I. Vinagre, J. L. Sanchez-Quesada, J. Sanchez-Hernandez et al., “Inflammatory biomarkers in type 2 diabetic patients: effect of glycemic control and impact of LDL subfraction phenotype,” Cardiovascular Diabetology, vol. 13, no. 1, p. 34, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Tuomi, A. Carlsson, H. Li et al., “Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies,” Diabetes, vol. 48, no. 1, pp. 150–157, 1999. View at Google Scholar
  24. H. Li, E. Lindholm, P. Almgren et al., “Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 diabetes,” The Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 2, pp. 574–582, 2001. View at Publisher · View at Google Scholar
  25. M. G. Myers Jr., L. M. Wang, X. J. Sun et al., “Role of IRS-1-GRB-2 complexes in insulin signaling,” Molecular and Cellular Biology, vol. 14, no. 6, pp. 3577–3587, 1994. View at Google Scholar
  26. A. Rezaei Farimani, M. Saidijam, M. T. Goodarzi et al., “Effect of resveratrol supplementation on the SNARE proteins expression in adipose tissue of stroptozotocin-nicotinamide induced type 2 diabetic rats,” Iranian Journal of Medical Sciences, vol. 40, no. 3, pp. 248–255, 2015. View at Google Scholar
  27. V. Fonseca, E. Chou, H. W. Chung, and C. Gerrits, “Economic burden of hypoglycemia with basal insulin in type 2 diabetes,” The American Journal of Managed Care, vol. 23, no. 2, pp. 114–122, 2017. View at Google Scholar
  28. Action to Control Cardiovascular Risk in Diabetes Study Group, H. C. Gerstein, M. E. Miller et al., “Effects of intensive glucose lowering in type 2 diabetes,” The New England Journal of Medicine, vol. 358, no. 24, pp. 2545–2559, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. ADVANCE Collaborative Group, A. Patel, S. MacMahon et al., “Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes,” The New England Journal of Medicine, vol. 358, no. 24, pp. 2560–2572, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. W. Duckworth, C. Abraira, T. Moritz et al., “Glucose control and vascular complications in veterans with type 2 diabetes,” The New England Journal of Medicine, vol. 360, no. 2, pp. 129–139, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. H. S. Sandhu, A. N. Butt, J. Powrie, and R. Swaminathan, “Measurement of circulating neuron-specific enolase mRNA in diabetes mellitus,” Annals of the New York Academy of Sciences, vol. 1137, pp. 258–263, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. P. J. Marangos and D. E. Schmechel, “Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells,” Annual Review of Neuroscience, vol. 10, pp. 269–295, 1987. View at Publisher · View at Google Scholar
  33. J. Li, M. Yan, Y. Zhang, M. Xie, L. Yan, and J. Chen, “Serum neuron-specific enolase is elevated as a novel indicator of diabetic retinopathy including macular oedema,” Diabetic Medicine : A Journal of the British Diabetic Association, vol. 32, no. 1, pp. 102–107, 2015. View at Publisher · View at Google Scholar · View at Scopus
  34. S. G. Kim, J. R. Hahm, D. K. Kim, S. R. Cho, and D. S. Choi, “Assessment of glycemic control in patients with type 2 diabetes mellitus treated with metformin-sulfonylurea combination: results of a multicenter, cross-sectional, observational study in Korea,” Journal of Diabetes Investigation, vol. 6, no. 3, pp. 317–324, 2015. View at Publisher · View at Google Scholar · View at Scopus
  35. A. A. Leontovich, R. V. Intine, and M. P. Sarras Jr., “Epigenetic studies point to DNA replication/repair genes as a basis for the heritable nature of long term complications in diabetes,” Journal of Diabetes Research, vol. 2016, Article ID 2860780, 10 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  36. T. Guo, L. Landsman, N. Li, and M. Hebrok, “Factors expressed by murine embryonic pancreatic mesenchyme enhance generation of insulin-producing cells from hESCs,” Diabetes, vol. 62, no. 5, pp. 1581–1592, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. C. Li and D. Kong, “Cancer risks from diabetes therapies: evaluating the evidence,” Pharmacology & Therapeutics, vol. 144, no. 1, pp. 71–81, 2014. View at Publisher · View at Google Scholar · View at Scopus
  38. A. Sekikawa, H. Fukui, T. Maruo, T. Tsumura, Y. Okabe, and Y. Osaki, “Diabetes mellitus increases the risk of early gastric cancer development,” European Journal of Cancer, vol. 50, no. 12, pp. 2065–2071, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. D. N. Miranda, D. K. Coletta, L. J. Mandarino, and G. Q. Shaibi, “Increases in insulin sensitivity among obese youth are associated with gene expression changes in whole blood,” Obesity, vol. 22, no. 5, pp. 1337–1344, 2014. View at Publisher · View at Google Scholar · View at Scopus