Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3β Inhibition-Induced Reduction of VEGF Release

Figure 1

The effect of silymarin on the migratory potential of untreated HBEC-5i. Human brain endothelial cells were treated with a range of silymarin concentrations, and the migration rate was measured. Representative images of the migrated cells (a) and a quantification of the migratory potential (b). Silymarin did not alter the migration rate of endothelial cells. Data are presented as mean ± SEM; indicates a significant difference from control. .

(a)

(b)