The Relation between Periodontopathogenic Bacterial Levels and Resistin in the Saliva of Obese Type 2 Diabetic Patients
Table 3
Real-time PCR quantification of Fusobacterium spp., P. gingivalis, T. forsythia, T. denticola, and A. actinomycetemcomitans in the saliva of obese patients (diabetics and nondiabetics) compared to the nonobese nondiabetic control.
Bacterial species
N range (mean ± SD) for each group
value
Nonobese ()
Obese diabetics ()
Obese nondiabetics ()
Fusobacterium spp.
3 × 10−5–6.9 × 10−2
12 × 10−5–100.7 × 10−2
60 × 10−5–80.7 × 10−2
0.003
(1.1 ± 1.6 × 10−2)
(11.5 ± 22.5 × 10−2)
(10.1 ± 20.5 × 10−2)
Positive cases per group
26
26
26
Total: 78 (100%)
P. gingivalis
0.45 × 10−5–0.7 × 10−2
1.87 × 10−5–13.49 × 10−2
0.06 × 10−5–46 × 10−2
<0.001
(0.08 ± 0.16 × 10−2)
(1.6 ± 3.4 × 10−2)
(5.2 ± 11.6 × 10−2)
Positive cases per group
26
26
24
Total: 76 (97.4%)
T. forsythia
0.5 × 10−5–0.14 × 10−2
3.7 × 10−5–2.3 × 10−2
17.1 × 10−5–14.46 × 10−2
<0.001
(0.04 ± 0.04 × 10−2)
(0.73 ± 0.74 × 10−2)
(1.9 ± 3.2 × 10−2)
Positive cases per group
24
26
26
Total: 76 (97.4%)
T. denticola
0.2 × 10−5–0.34 × 10−3
0.1 × 10−5–4.6 × 10−3
0.2 × 10−5–8.2 × 10−3
0.068
(8.9 ± 9.9 × 10−5)
(37.99 ± 92.8 × 10−5)
(58.9 ± 168.2 × 10−5)
Positive cases per group
20
25
24
Total: 69 (88.5%)
A. actinomycetemcomitans
0.3 × 10−4–2.1 × 10−4
0.2 × 10−4–4.9 × 10−3
6.8 × 10−4–24.5 × 10−3
0.097
(0.5 ± 0.8 × 10−4)
(0.9 ± 1.7 × 10−4)
(5.7 ± 8.9 × 10−4)
Positive cases per group
7
8
9
Total: 24 (30.8%)
N = fold difference in the number of the target organism-specific gene copies relative to the number of 16S rRNA gene copies. Significant difference ().
