Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice

Figure 3

Overexpression of GGT1 in the liver had no effect on glucose tolerance. (a) IPGTT was performed and the blood glucose was measured at the indicated time points (); (b) AUC of the IPGTT curve. (c) IPGTT was performed in GGT1-L-OE mice and GGT1-L-OE-sTop mice which are treated with GGsTop, a highly selective GGT inhibitor, and the AUC was evaluated (d).

(a)

(b)

(c)

(d)