Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice

Figure 2

Effect of GA on kidney pathology in db/db mice. Representative sections obtained from the kidneys of mice (8 weeks old) in each group were stained with (a) HE ×400, electron microscopy (TEM) ×2000, and PAS ×400, Masson staining (blue) ×400. (b) Quantitative estimates of the mesangial fractional area (%). (c) Quantitative assessment of the interstitial collagen area (%). Values are shown as means ± SD. .

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