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Journal of Diabetes Research
Volume 2017, Article ID 3141678, 10 pages
Research Article

Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics

1Department of Ophthalmology, Toho University Omori Medical Center, Tokyo, Japan
2Cardiovascular Center, Toho University Sakura Medical Center, Chiba, Japan

Correspondence should be addressed to Tomoaki Shiba;

Received 25 April 2017; Revised 12 July 2017; Accepted 1 August 2017; Published 5 September 2017

Academic Editor: Patrizio Tatti

Copyright © 2017 Tomoaki Shiba et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To clarify whether the incidence of metabolic syndrome (MetS) and the overlap of MetS components are affecting the ocular circulation shown by laser speckle flowgraphy (LSFG). Materials and Methods. We studied 76 consistent patients. Blowout score (BOS) and blowout time (BOT), which are the pulse waveform analysis parameters, and mean blur rate (MBR) using LSFG in the optic nerve head (ONH) and choroid were evaluated. Throughout, the ONH was separated out from the vessels and tissue for analysis and MBRs in the ONH were divided into four sections (superior, temporal, inferior, and nasal). Results. Thirty-two patients were diagnosed having Mets. MBR-Tissue (), MBR-All (), MBR-Choroid (), and BOS-Choroid () were significantly lower in patients with MetS than in the patients without MetS. Multiple-regression analysis revealed the temporal side of MBR-Tissue and BOS-Choroid which were identified as factors contributing independently to the overlap of the MetS components. Multiple-regression analysis also revealed that the MetS components were identified to be factors independently contributing to the BOS-Choroid and temporal side of MBR-Tissue. Conclusion. Our study clarified that the incidence of MetS and the overlap of the MetS components are significantly affecting the ONH and choroidal microcirculation.