Quercetin Improves Glucose and Lipid Metabolism of Diabetic Rats: Involvement of Akt Signaling and SIRT1
Table 1
Blood biochemical parameters of experimental diabetic rats after 12 weeks of quercetin treatment ().
Group
FBG (mmol·L−1)
GSP (mmol·L−1)
HbA1c (OD·10 g−1)
TC (mmol·L−1)
TG (mmol·L−1)
LDL-C (mmol·L−1)
HDL-C (mmol·L−1)
Control
5.27 ± 0.31
1.61 ± 0.13
18.937 ± 3.83
1.41 ± 0.25
0.69 ± 0.13
0.31 ± 0.08
0.62 ± 0.12
Diabetes
25.26 ± 3.45bb
4.68 ± 0.77bb
38.83 ± 8.11bb
4.33 ± 1.29bb
4.61 ± 1.33bb
5.35 ± 1.68b
0.59 ± 0.20
QU-low
22.98 ± 2.16abb
2.56 ± 0.67abb
26.251 ± 5.23aa
2.12 ± 0.29aa
1.03 ± 0.63aa
0.98 ± 0.37aa
0.70 ± 0.19
QU-high
22.76 ± 3.61aabb
2.23 ± 0.46aa
25.97 ± 5.13aab
1.49 ± 0.41aa
0.98 ± 0.49aa
0.84 ± 0.14a
0.66 ± 0.22
Pioglitazone
16.71 ± 0.81abb
1.98 ± 0.33aa
29.16 ± 4.22aab
1.46 ± 0.28aa
0.96 ± 0.56aa
0.635 ± 0.26a
0.68 ± 0.17
Data are represented as mean ± S.D. FBG: fasting blood glucose; GSP: glycosylated serum protein; HbA1c: glycosylated hemoglobin A1c; TC: serum total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol. versus control, versus control, versus diabetes, and versus diabetes.