Quercetin Improves Glucose and Lipid Metabolism of Diabetic Rats: Involvement of Akt Signaling and SIRT1

Table 1

Blood biochemical parameters of experimental diabetic rats after 12 weeks of quercetin treatment ().

Group	FBG (mmol·L^−1)	GSP (mmol·L^−1)	HbA1c (OD·10 g^−1)	TC (mmol·L^−1)	TG (mmol·L^−1)	LDL-C (mmol·L^−1)	HDL-C (mmol·L^−1)
Control	5.27 ± 0.31	1.61 ± 0.13	18.937 ± 3.83	1.41 ± 0.25	0.69 ± 0.13	0.31 ± 0.08	0.62 ± 0.12
Diabetes	25.26 ± 3.45^bb	4.68 ± 0.77^bb	38.83 ± 8.11^bb	4.33 ± 1.29^bb	4.61 ± 1.33^bb	5.35 ± 1.68^b	0.59 ± 0.20
QU-low	22.98 ± 2.16^abb	2.56 ± 0.67^abb	26.251 ± 5.23^aa	2.12 ± 0.29^aa	1.03 ± 0.63^aa	0.98 ± 0.37^aa	0.70 ± 0.19
QU-high	22.76 ± 3.61^aabb	2.23 ± 0.46^aa	25.97 ± 5.13^aab	1.49 ± 0.41^aa	0.98 ± 0.49^aa	0.84 ± 0.14^a	0.66 ± 0.22
Pioglitazone	16.71 ± 0.81^abb	1.98 ± 0.33^aa	29.16 ± 4.22^aab	1.46 ± 0.28^aa	0.96 ± 0.56^aa	0.635 ± 0.26^a	0.68 ± 0.17

Data are represented as mean ± S.D. FBG: fasting blood glucose; GSP: glycosylated serum protein; HbA1c: glycosylated hemoglobin A1c; TC: serum total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol. versus control, versus control, versus diabetes, and versus diabetes.