Changes in the Diaphragm Lipid Content after Administration of Streptozotocin and High-Fat Diet Regime

Table 3

Effects of high-fat diet (HFD), streptozotocin (STZ), and myriocin (M) on diaphragm triacylglycerol content (mean ± SEM, per group). Difference versus Ctrl (); ^#within group difference (M+ versus M−) (). ND: not detected.

	TAG fatty acid composition (nmol/g of wet tissue)
	Ctrl		STZ		HFD
	M−	M±	M−	M±	M−	M±
Myristic acid (14 : 0)	1730.1 ± 82.76	838.9 ± 48.91^#	83.3 ± 5.3	45.4 ± 3.27^#	1607.6 ± 159.74	1148.5 ± 54.63^#
Palmitic acid (16 : 0)	21948.8 ± 675.9	10,583 ± 605.94^#	1850.9 ± 188.69	802.6 ± 104.53^#	23838.9 ± 3244	17682.7 ± 863
Palmitooleic acid (16 : 1)	7945.4 ± 395.71	1992.8 ± 140.51^#	74.7 ± 3	40 ± 7.66^#	2731.7 ± 423.93	2427 ± 356.94
Stearic acid (18 : 0)	2394.1 ± 101.64	1484.9 ± 46.57^#	400.8 ± 22.51	239.9 ± 23.26^#	6880.6 ± 635.14	4798.4 ± 163.82^#
Oleic acid (18:1n9c)	17958.7 ± 595.07	9165.1 ± 266.3^#	1455.8 ± 130.44	638.2 ± 72.06^#	38246.9 ± 3548.67	28022.8 ± 1580.96^#
Linoleic acid (18:2n6c)	7011 ± 472.89	10364.3 ± 531.09^#	2092.5 ± 161.89	865.3 ± 125.93^#	24048.4 ± 2718.94	19,753 ± 1685.25
Arachidic acid (20 : 0)	38.2 ± 3.49	28.8 ± 1.82	31.5 ± 1.19	17.3 ± 1.51^#	82.3 ± 4.56	86 ± 6.2
Linolenic acid (C18:9n3)	580.7 ± 40.41	674.5 ± 53.83	118.3 ± 7.24	57.6 ± 9.51^#	1440.7 ± 194.71	1057.3 ± 118.49
Behenic acid (22 : 0)	25.1 ± 4.29	15.4 ± 0.86	30.8 ± 1.92	17.2 ± 2.06^#	47.4 ± 3.67	53.2 ± 6.21
Arachidonic acid (20:4n6)	177.3 ± 15.77	233.2 ± 22.01^#	110.6 ± 16.02	71 ± 12.28	300.9 ± 12.57	211.9 ± 13.32^#
Lignoceric acid (24 : 0)	39.6 ± 1.61	20.8 ± 1.35^#	42.7 ± 15.3	19.7 ± 0.67^#	68.4 ± 2.94	74.6 ± 9.86
Eicosapentaenoic acid (20:5n3)	16.0 ± 2.74	10.1 ± 0.85	9.7 ± 1.39	4.6 ± 0.79^#	37.4 ± 1.11	35.4 ± 5.69
Nervonic acid (24 : 1)	17.4 ± 1.82	9.6 ± 0.97^#	15.3 ± 0.65	8.1 ± 0.65^#	39.9 ± 3.59	46.3 ± 5.96
Docosahexaenoic acid (22:6n3)	129.2 ± 14.46	174.2 ± 12.55	355.3 ± 28.67	228.2 ± 41.62^#	272.3 ± 19.49	203.8 ± 19.63
SAT	26175.8 ± 787.38	12971.7 ± 620.66^#	2439.9 ± 201.06	1142.1 ± 128.61^#	32525.1 ± 4017.93	23843.3 ± 1055.22
UNSAT	33835.8 ± 1081.05	22623.7 ± 659.81^#	4232.2 ± 337.45	1912.9 ± 253.3^#	67118.3 ± 6608.54	51757.6 ± 2808.14^#
Total	60011.6 ± 1817.28	35595.4 ± 1203.21^#	6672.1 ± 535.69	3055 ± 379.25^#	99643.4 ± 10495.24	75600.9 ± 3772.94^#