Urinary Microvesicle-Bound Uromodulin: A Potential Molecular Biomarker in Diabetic Kidney Disease
Table 1
Baseline anthropometric and biochemical characteristics.
Parameter
Control group
DM group
DN1 group
DN2 group
Number ()
31
46
32
22
Age (year)
56.5 ± 7.85
55.02 ± 11.41
52.79 ± 15.12
51.56 ± 17.09
Gender (male/female)
15/16
28/18
13/19
12/10
UACR (mg/g)
5.75 ± 2.63
9.8 ± 4.38
91.6 ± 46.44
642.79 ± 332.86
HbA1c (%)
4.62 ± 0.43
8.45 ± 2.72
8.98 ± 2.56
9.63 ± 2.3
CR (mmol/l)
51.13 ± 13.17
61.78 ± 15.21
70.58 ± 21.19
95.03 ± 46.11
BUN (mmol/l)
4.33 ± 0.84
4.21 ± 0.99
6.75 ± 2.97
6.03 ± 2.41
Systolic blood pressure (mmHg)
139.5 ± 12.66
142.68 ± 20.82
138.7 ± 14.8
162.57 ± 19.97
Diastolic blood pressure (mmHg)
79.25 ± 10.78
82.47 ± 9.87
81.5 ± 12.66
83.43 ± 9.62
CH (mmol/l)
4.83 ± 0.92
4.9 ± 1.62
4.13 ± 1.3
5.58 ± 2.3
TG (mmol/l)
2.03 ± 0.95
1.68 ± 0.94
1.78 ± 0.43
1.53 ± 0.76
LDL-C (mmol/l)
1.78 ± 0.4
2.76 ± 0.74
2.21 ± 0.8
2.22 ± 0.53
HDL-C (mmol/l)
1.24 ± 0.57
1.3 ± 0.3
1.08 ± 0.25
1.09 ± 0.3
versus control group; versus DM group; versus DN1 group. DM = type 2 diabetes mellitus with normoalbuminuria; DN1 = type 2 diabetes mellitus with microalbuminuria; DN2 = type 2 diabetes mellitus with macroalbuminuria; UACR = urinary albumin/creatinine ratio; HbA1c = glycosylated hemoglobin; TG = triglyceride; CH = cholesterol; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol; CR = creatinine; BUN = blood urea nitrogen.
