Reducing Caloric Intake Prevents Ischemic Injury and Myocardial Dysfunction and Affects Anesthetic Cardioprotection in Type 2 Diabetic Rats
Table 1
Characteristics after 4 and 8 weeks of diet intervention without sevoflurane exposure.
4 weeks
8 weeks
Control diet
Western diet
Control diet
Western diet
Reversion
Caloric intake [kcal/100 gBW]
Plasma glucose [mmol/L]
Plasma insulin [pmol/L]
Plasma free fatty acids [mmol/L]
Plasma triglycerides [mmol/L]
Plasma HDL cholesterol [mg/dL]
Plasma LDL/VLDL cholesterol [mg/dL]
Hematocrit [%]
Bodyweight [g]
Heart weight [g]
n.d.
n.d.
Liver weight [g]
n.d.
n.d.
Epididymal fat weight [g]
n.d.
n.d.
Perirenal fat weight [g]
n.d.
n.d.
Tibia length [mm]
n.d.
n.d.
Data are mean ± SD, weeks: Student’s -test, versus control diet; 8 weeks: one-way ANOVA with Bonferroni post hoc test, versus control diet, versus western diet, and n.d.: nondetermined.