Research Article

Reducing Caloric Intake Prevents Ischemic Injury and Myocardial Dysfunction and Affects Anesthetic Cardioprotection in Type 2 Diabetic Rats

Table 2

Myocardial function after 4 and 8 weeks of diet intervention without sevoflurane exposure.

4 weeks8 weeks
Control dietWestern dietControl dietWestern dietReversion

Heart rate [bpm]
LV mass [mg]
LV dimensions
 Diastolic lumen diameter [mm]
 Systolic lumen diameter [mm]
 Diastolic wall thickness [mm]
 Systolic wall thickness [mm]
LV diastolic function
 E deceleration time [ms]
 Isovolumic relaxation time [ms]n.d.n.d.n.d.

Data are mean ± SD, and 4 weeks: Student’s -test, versus control diet, versus control diet; 8 weeks: one-way ANOVA with Bonferroni post hoc analyses; versus control diet, versus control diet, and versus western diet. LV: left ventricular.