Research Article

Retinal Photoreceptors and Microvascular Changes in Prediabetes Measured with Adaptive Optics (rtx1™): A Case-Control Study

Table 1

Group characteristics and results of the blood parameters and BMI in the groups.

TotalPrediabeticControl
n (%)n (%)n (%)

Number of subjects34 (100)12 (35)22 (65)
Women22 (65)9 (75)13 (59)
Characteristicsm ± SDm ± SDm ± SD value
Age (years)52.1 ± 11.952.6 ± 10.042.4 ± 14.30.8733
BMI (kg/m2)26.1 ± 3.930.4 ± 5.725 ± 20.0030
AL (mm)24.17 ± 1.5223.78 ± 1.5224.24 ± 1.450.3568
Blood parametersm ± SDm ± SDm ± SD value
FPG (mg/dL)91 ± 10102 ± 1188 ± 60.0144
FPG (mmol/L)5.0 ± 0.75.7 ± 064.8 ± 0.60.0038
2-h OGTT (mg/dL)107 ± 27141 ± 2396 ± 170.0001
HbA1c (%)5.46 ± 0.265.56 ± 0.365.43 ± 0.220.4227
Insulin (mIU/mL)8.4 ± 6.512.7 ± 12.47.1 ± 3.10.3215
Total cholesterol (mg/dL)117 ± 24174 ± 41168 ± 170.6142
TG (mg/dL)99 ± 33115 ± 4494 ± 280.2591
LDL (mg/dL)114 ± 27117 ± 27113 ± 270.7994
HDL (mg/dL)51 ± 1052 ± 1051 ± 100.6780

Mann–Whitney U test. m: mean; SD: standard deviation; AL: mean axial length; FPG: fasting plasma glucose; 2-h OGTT: oral glucose tolerance test with 75 g of glucose; HbA1c: glycated hemoglobin A1c; TG: triglyceride; LDL: low-density lipoprotein cholesterol; HDL: high-density lipoprotein cholesterol; BMI: body mass index.