Rs46522 in the Ubiquitin-Conjugating Enzyme E2Z Gene Is Associated with the Risk of Coronary Artery Disease in Individuals of Chinese Han Population with Type 2 Diabetes
Table 1
Clinical characteristics of CAD group and non-CAD group.
CAD group
Non-CAD group
value
Gender (M/F)
257/133
118/158
<0.001
Age (yr)
64 (57–72)
61 (55–69)
0.001
BMI (kg/m2)
26.39 ± 3.37
26.19 ± 3.61
0.472
History of T2D (yr)
8 (3–13)
7 (3–12)
0.769
History of hypertension (%)
76.2
70.7
0.110
Fasting plasma glucose (mmol/L)
6.45 (5.59–7.80)
6.42 (5.47–7.64)
0.263
HbA1c (%)
6.8 (6.3–7.8)
6.7 (6.1–7.5)
0.080
Triglyceride (mmol/L)
1.39 (0.96–1.93)
1.40 (0.97–2.03)
0.615
Total cholesterol (mmol/L)
4.00 ± 1.04
4.24 ± 0.92
0.004
LDL-C (mmol/L)
2.26 (1.79–2.91)
2.45 (1.91–2.94)
0.071
HDL-C (mmol/L)
0.95 (0.80–1.10)
1.03 (0.86–1.23)
<0.001
Smoking status (%)
51.5
34.1
<0.001
BMI: body mass index; FPG: fasting plasma glucose; CAD: coronary artery disease; T2D: type 2 diabetes; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol. The fasting plasma glucose values, lipid profile, and HbA1c were after intervention.
