Research Article

Rs46522 in the Ubiquitin-Conjugating Enzyme E2Z Gene Is Associated with the Risk of Coronary Artery Disease in Individuals of Chinese Han Population with Type 2 Diabetes

Table 3

Genotype distribution of rs46522 between CAD and non-CAD groups in codominant inheritance model.

Genotype frequencyCAD group
n (%)
Non-CAD group
n (%)
OR (95%CI) valueOR (95%CI) value

T/T194 (49.7)115 (41.8)
C/T165 (42.3)135 (49.1)1.380 (0.998–1.908)0.0511.673 (1.088–2.570)0.019
C/C31 (7.9)25 (9.1)1.360 (0.765–2.418)0.2931.182 (0.799–1.749)0.402

CAD: coronary artery disease. OR, 95%CI, and p were after adjustment with age, gender, history of hypertension and diabetes, smoking status, BMI, fasting glucose, and lipid levels.