Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy

Figure 1

Effects of high glucose (HG) on the viability and apoptosis of HRECs and ARPE-19 cells. (a, b) Time-dependent increase in hyperglycemia-induced inhibition of HRECs and RPE proliferation. (c, d) Representative images of HRECs and RPE cells treated with normal glucose (NG) or HG. The number of apoptotic cells harboring condensed or fragmented nuclei (yellow, arrowheads) increased along with an increase in HG-treatment time. (e, f) Statistical analysis of apoptotic HRECs and RPE cells under different conditions. Quantification was performed using ImageJ software. ; ; .

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