High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report

Table 2

Operating parameters for serum AGE measurement using a QTRAP 5500 mass spectrometer equipped with an electrospray ion source operating in the positive ion mode.

Compound	Retention time (min)	Precursor ion (m/z)	Product ion (m/z)	DP (V)	CE (V)	CXP (V)
CEL	5.64	219.1	84.1	111	27	6
CML	6.01	205.1	84.1	76	25	10
MG-H1	9.09	229.1	70.1	46	30	8
CEL-d4	5.65	223.1	88.1	111	27	6
CML-d4	5.99	209.1	88.1	76	25	10
MG-H1-d3	9.07	232.1	70.1	46	30	8

DP: declustering potential; CE: collision energy; CXP: collision cell exit potential; CEL: carboxyethyllysine; CML: carboxymethyllysine; MG-H1: methyl-glyoxal-hydro-imidazolone.