Research Article
Decreased Cardiovascular Risk after Roux-en-Y Gastric Bypass Surgery in Chinese Diabetic Patients with Obesity
Table 2
Changes of cardiometabolic factors before and after RYGB (
).
| | Parameters | Before RYGB | After RYGB (18 months) | value |
| | Weight (kg) | 94.70 ± 21.95 | 70.66 ± 11.48 | <0.001 | | BMI (kg/m2) | 34.20 ± 6.22 | 25.89 ± 3.89 | <0.001 | | WHR | 1.00 ± 0.10 | 0.91 ± 0.09 | 0.002 | | SBP (mmHg) | 136.65 ± 21.56 | 122.20 ± 10.18 | 0.001 | | DBP (mmHg) | 85.50 ± 10.56 | 79.15 ± 1.16 | 0.015 | | FPG (mmol/L) | 10.57 ± 3.46 | 5.59 ± 0.84 | <0.001 | | PPG (mmol/L) | 16.59 ± 4.31 | 8.55 ± 1.80 | <0.001 | | HbA1c (%) | 8.48 ± 1.49 | 5.89 ± 0.62 | <0.001 | | FINS (mU/L) | 19.17 (15.7, 26.8) | 6.61 (5.1, 12.2) | <0.001 | | PINS (mU/L) | 44.48 (27.2, 63.4) | 24.76 (15.4, 36.6) | 0.003 | | Fasting C-peptide (nmol/L) | 1.21 ± 0.37 | 0.76 ± 0.23 | <0.001 | | PCP (nmol/L) | 2.52 ± 1.14 | 2.03 ± 0.88 | 0.002 | | HOMA-IR | 8.41 (5.7, 14.3) | 1.82 (1.14, 3.11) | <0.001 | | HOMA-beta (%) | 54.83 (39.3, 100.4) | 80.7 (146.8, 119.1) | 0.391 | | TC (mmol/L) | 6.59 (5.2, 8.0) | 4.77 (4.2, 5.2) | <0.001 | | TG (mmol/L) | 2.52 (1.7, 3.9) | 1.14 (0.8, 1.6) | <0.001 | | LDL-C (mmol/L) | 3.08 ± 1.15 | 2.94 ± 0.91 | 0.642 | | HDL-C (mmol/L) | 1.21 (0.8, 1.7) | 2.25 (1.7, 2.4) | <0.001 |
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Note. WHR: waist-hip ratio; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; PPG: 2-hour postprandial glucose; FINS: fasting insulin; PINS: 2-hour postprandial insulin; FCP: fasting C-peptide; PCP: 2-hour postprandial C-peptide; HbA1c: hemoglobin A1c; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model of assessment for insulin resistance index; HOMA-β: HOMA of beta cell function. Data represent means ± SD or M (P25, P75). : significant difference.
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