Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus

<div>Effects of HMS5552 on insulin immunoreactivity in the rat pancreas. Pancreas tissue sections stained with anti-insulin antibody are shown at 200x magnification (a), and the number of insulin-immunopositive cells in islets was analyzed (b). HMS-L group, low-dose (10 mg/kg) HMS5552-treated diabetic group; HMS-H group, high-dose (30 mg/kg) HMS5552-treated diabetic group. 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Journal of Diabetes Research

fig5

Figure 5

Figure 5: Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus 