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Journal of Diabetes Research
Volume 2017 (2017), Article ID 6216205, 8 pages
Research Article

Synergistic Effect of the MTHFR C677T and EPHX2 G860A Polymorphism on the Increased Risk of Ischemic Stroke in Chinese Type 2 Diabetic Patients

1Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
2Clinical Laboratory, China-Japan Friendship Hospital, Beijing, China
3Beijing Key Lab Immune-Mediated Inflammatory Diseases, Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, China
4Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China

Correspondence should be addressed to Yongtong Cao; moc.anis@29gnotgnoyoac and Ping Li; moc.361@5768pl

Received 13 January 2017; Revised 14 February 2017; Accepted 7 March 2017; Published 20 March 2017

Academic Editor: Tim J. Schulz

Copyright © 2017 Liang Ma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In terms of the MTHFR C677T genotype, Hcy level is associated with MTHFR C677T polymorphism (P = .0497), and TT genotype was associated with higher Hcy level compared with the CC genotype. In terms of the EPHX2 G860A genotype, Hcy level was not associated with EPHX2 rs751141 polymorphism (P = .62) (Supplementary Table 1).

  1. Supplementary Material