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Journal of Diabetes Research
Volume 2017, Article ID 6305370, 5 pages
https://doi.org/10.1155/2017/6305370
Research Article

Therapeutic Effects of Static Magnetic Field on Wound Healing in Diabetic Rats

1Central Laboratory, Medical School of Yangtze University, Hubei 434003, China
2Department of Endocrinology, Central Hospital of Jingzhou City, Hubei 434001, China
3Department of Endocrinology, The First Affiliated Hospital of Yangtze University, Hubei 434000, China
4Department of Internal Medicine, The First Clinical Medical School of Yangtze University, Hubei 434000, China

Correspondence should be addressed to Peng Yun; moc.361@321py_dyjt and Ting Gong; moc.qq@62051782

Received 3 January 2017; Accepted 27 February 2017; Published 26 March 2017

Academic Editor: Paul Valensi

Copyright © 2017 Jing Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To investigate the effects of static magnetic field (SMF) on cutaneous wound healing of Streptozotocin- (STZ-) induced diabetic rats. Methods. 20 STZ-induced diabetic rats were randomly divided into two groups (10 in each group): diabetic rats with SMF exposure group which were exposed to SMF by gluing one magnetic disk of 230 mT intensity and diabetic rats with sham SMF exposure group (sham group). 10 normal Wistar rats were used as the control group. One open circular wound with 2 cm diameter in the dorsum was generated on both normal and diabetic rats and then covered with sterile gauzes. Wound healing was evaluated by wound area reduction rate, mean time to wound closure, and wound tensile strength. Results. The wound area reduction rate in diabetic rats in comparison with the control group was significantly decreased (). Compared with sham magnet group, diabetic rats under 230 mT SMF exposure demonstrated significantly accelerated wound area reduction rate on postoperative days 7, 14, and 21 and decreased gross time to wound closure (), as well as dramatically higher wound tissue strength () on 21st day. Conclusion. 230 mT SMF promoted the healing of skin wound in diabetic rats and may provide a non-invasive therapeutic tool for impaired wound healing of diabetic patients.