Clinical Study

Efficacy of Administration of an Angiotensin Converting Enzyme Inhibitor for Two Years on Autonomic and Peripheral Neuropathy in Patients with Diabetes Mellitus

Table 2

Changes in cardiovascular autonomic reflex tests during the study in patients who received quinapril (group A) and in those who did not (group B).

⁢Group A ()⁢Group B ()p  (group A versus group B at end of treatment)
BaselineEnd of treatmentp
(versus baseline)
BaselineEnd of treatmentp
(versus baseline)

E/I index0.0110.007<0.001
MCR0.0060.01<0.001
SD0.004<0.05<0.001
Valsalva indexNSNSNS
30 : 15 indexNS<0.05<0.001
OHNS0.018<0.001

E/I: expiration/inspiration; MCR: mean circular resultant; SD: standard deviation; OH: orthostatic hypotension.