Direct and Indirect Effects of Serum Uric Acid on Blood Sugar Levels in Patients with Prediabetes: A Mediation Analysis

Table 2

Causal effects of uric acid, waist circumference, and glycemic parameters.

Effects	Pathway	β	SE	Z	value	Bias	95% CI
Fasting plasma glucose
Indirect	➔➔UA WC FPG	0.082	0.037	2.23	0.026	−0.002	0.010, 0.154
Direct	➔UA FPG	0.413	0.185	2.23	0.026	0.005	0.049, 0.776
HbA1c
Indirect	➔➔UA WC HbA1c	0.006	0.002	3.43	0.001	−0.0002	0.003, 0.010
Direct	➔UA HbA1c	0.014	0.009	1.59	0.111	−0.0003	−0.003, 0.030

CI: confidence interval; FPG: fasting plasma glucose; SE: standard error; UA: serum uric acid; WC: waist circumference.