Gene Expression Profiling Identifies Downregulation of the Neurotrophin-MAPK Signaling Pathway in Female Diabetic Peripheral Neuropathy Patients

Table 4

Expression of TLR family genes.

Gene symbol	Log2 (ratio)			value
	DM/CN	DPN/CN	DPN/DM	DM/CN	DPN/CN	DPN/DM
TLR1	1.744	2.033	0.289	4.40E−04	5.22E−05	0.516
TLR2	2.175	2.056	−0.119	9.34E−04	1.05E−05	0.818
TLR4	2.861	4.254	1.393	1.73E−05	5.71E−09	1.38E−02
TLR5	2.213	3.682	1.469	6.31E−03	2.55E−11	0.054
TLR6	2.908	2.169	−0.738	4.24E−05	5.15E−06	0.213
TLR7	1.677	3.475	1.799	1.44E−02	2.72E−09	6.67E−03
TLR8	2.041	2.785	0.745	1.31E−04	2.61E−06	0.109
TLR9	1.623	1.135	−0.488	3.37E−04	3.82E−04	0.232

TLR3 and TLR10 were removed after data normalization because of the low fluorescent intensity of probes.