Transcriptional Profile of Kidney from Type 2 Diabetic db/db Mice

Table 2

Top 10 enriched GO terms for DEGs sorted by value (ascending).

GOID	GO term	Term value corrected with Bonferroni step down	Genes cluster #1	Genes cluster #2
GO:0030193	Regulation of blood coagulation		[Apoe, Ptger3, Serpine2]	[Apoh, Cd209a, Cd36, Hrg, Proc, Rpl3, Serpinf2, Tc2n]
GO:0015291	Secondary active transmembrane transporter activity		[Gm6614, Slc22a29, Slc5a1, Slc6a12, Slc7a12, Slc8a1, Slco4a1]	[Mfsd2a, Slc1a4, Slc22a19, Slc22a26, Slc22a28, Slc6a9, Slc7a13, Slc9a8, Slco1a1, Tmco3]
GO:0008514	Organic anion transmembrane transporter activity		[Abcc4, Gm6614, Slc22a29, Slc6a12, Slc7a12, Slco4a1]	[Slc1a4, Slc22a19, Slc22a26, Slc22a28, Slc22a7, Slc6a9, Slc7a13, Slco1a1]
GO:0019216	Regulation of lipid metabolic process		[Abhd6, Angptl3, Angptl8, Apoc1, Apoe, C3, Cyp17a1, Cyp27b1, Fabp1, Pdk1, Pik3r3, Prox1]	[Akr1c18, Apoh, Esr1, Kcnma1, Nt5e]
GO:0004497	Monooxygenase activity		[Agmo, Cyp17a1, Cyp27b1, Cyp2d22, Cyp2d26, Cyp4a14]	[Akr1c18, Cyp2a4, Cyp2j13, Cyp51, Cyp7b1, Fmo5]
GO:0015297	Antiporter activity		[Slc22a29, Slc7a12, Slc8a1]	[Slc22a19, Slc22a26, Slc22a28, Slc7a13, Slc9a8, Tmco3]
GO:0009636	Response to toxic substance		[Aoc1, Apoe, Cyp17a1, Ephx1, Fabp1, Gria3, Gsta4, Gsto1, Ltc4s, Maob, Nupr1]	[Bdh1, Ccl5, Cd36, Ubiad1]
GO:0015908	Fatty acid transport		[Abcc4, Apoe, Fabp1]	[Ace, Cd36, Crot, Mfsd2a]
GO:0016765	Transferase activity, transferring alkyl or aryl (other than methyl) groups		[BC021614, Gm10639, Gsta4, Gsto1, Ltc4s]	[Agps, Ubiad1]
GO:0022600	Digestive system process	3	[Cyp27b1, Fabp1, Ptger3, Slc5a1]	[Cckar, Cd36, Chrm3, Kcnma1]