Research Article

Interaction of Pubertal Development and Metabolic Control in Adolescents with Type 1 Diabetes Mellitus

Table 1

Clinical characteristics of 1294 type 1 diabetic patients, depending on sex and metabolic control (data expressed as median and interquartile range).

AllFemaleMaleHbA1c < 7.5%HbA1c > 7.5%

n1294630664647647
Age at study start (yr)7.25 (7.21; 7.29)7.25 (7.22; 7.29)7.25 (7.21; 7.29)7.25 (7.21; 7.29)7.25 (7.22; 7.29)
Age at end of study (yr)15.75 (15.7; 15.79)15.74 (15.69; 15.79)15.75 (15.7; 15.79)15.75 (15.7; 15.78)15.74 (15.69; 15.79)
Diabetes duration at study start (yr)2.56 (1.23; 4.09)2.46 (1.15; 4.08)2.63 (1.30; 4.15)2.40 (1.22; 3.91)2.84 (1.26; 4.29)
Diabetes duration at study end (yr)11.07 (9.7; 12.58)10.94 (9.66; 12.57)11.13 (9.78; 12.61)10.9 (9.67; 12.37)11.3 (9.71; 12.79)
Height SDS at study start0.17 (−0.45; 0.85)0.17 (−0.43; 0.84)0.17 (−0.45; 0.85)0.25 (−0.32; 0.92)0.12 (−0.51; 0.75)
Height SDS at study end0.01 (−0.64; 0.65)0.04 (−0.65; 0.69)−0.02 (−0.64; 0.62)0.19 (−0.44; 0.80)−0.18 (−0.79; 0.48)
BMI-SDS at study start0.37 (−0.18; 0.82)0.38 (−0.15; 0.84)0.35 (−0.21; 0.78)0.36 (−0.20; 0.82)0.39 (−0.17; 0.82)
BMI-SDS at study end0.39 (−0.16; 0.89)0.61 (0.12; 1.06)0.18 (−0.40; 0.68)0.30 (−0.24; 0.86)0.46 (−0.07; 0.92)
HbA1c at study start (%)7.17 (6.51; 7.89)7.17 (6.51; 7.92)7.15 (6.51; 7.88)6.77 (6.22; 7.20)7.72 (7.13; 8.32)
HbA1c at study end (%)8.08 (7.33; 9.09)8.12 (7.33; 9.19)8.04 (7.33; 8.99)7.42 (6.87; 7.98)8.94 (8.18; 9.92)