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Journal of Diabetes Research
Volume 2017, Article ID 9031079, 11 pages
https://doi.org/10.1155/2017/9031079
Research Article

Leptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women

1Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile
2Carrera de Nutrición y Dietética, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
3School of Food Engineering, Universidad Austral de Chile, Valdivia, Chile

Correspondence should be addressed to José Luis Santos; lc.cup.dem@sotnasj

Received 7 December 2016; Accepted 13 March 2017; Published 25 May 2017

Academic Editor: Konstantinos Kantartzis

Copyright © 2017 Carolina Bravo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Figure 1. Association between insulin sensitivity indexes with body mass index (BMI) in a cross-sectional sample of 58 Chilean normoglycaemic women. Supplemental Figure 2. Association between leptin, total adiponectin and high molecular weight adiponectin with body mass index (BMI) in a cross-sectional sample of 58 Chilean normoglycaemic women. HMWA: High Molecular Weight Adiponectin. Supplemental Figure 3. Associations between log of Leptin, Total Adiponectin and High Molecular Weight Adiponectin ratio with sensitivity insulin indexes in a cross-sectional sample of 58 Chilean normoglycaemic women. HMWA: High Molecular Weight Adiponectin. Supplemental Figure 4. Box plots showing thirds of leptin, total adiponectin and high molecular weight adiponectin with insulin sensitivity indexes (HOMA-S and CSi) in a cross-sectional sample of 58 Chilean normoglycaemic women. Supplemental Figure 5. Box plots showing thirds of leptin/total adiponectin and leptin/high molecular weight adiponectin with insulin sensitivity indexes (HOMA-S and CSi) index in a cross-sectional sample of 58 Chilean normoglycaemic women. Supplemental Table 1. Association between insulin sensitivity indexes with plasma leptin, total adiponectin, HMW-adiponectin and leptin/adiponectin ratios #. Supplemental Table 2. ROC curve analysis to evaluate the discriminatory capacity of leptin, total adiponectin, HMWA, LAR and leptin/HMWA ratio in relation to insulin sensitivity indexes.

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