Polymorphisms in the Glucagon-Like Peptide 1 Receptor (GLP-1R) Gene Are Associated with the Risk of Coronary Artery Disease in Chinese Han Patients with Type 2 Diabetes Mellitus: A Case-Control Study

Table 1

Clinical characteristics of CAD-positive and control patients with T2DM.

	CAD-pos.	Controls
	394	217
Male, (%)	274 (69.5)	97 (44.7)	<0.001
Age (y)	61.38 ± 10.13	62.19 ± 10.28	0.384
T2DM duration (y)	6.0 (1.0–12.0)	6.0 (2.0–10.0)	0.912
BMI (kg/m^2)	26.1 ± 3.55	25.9 ± 3.65	0.521
HbA1c (%)	7.28 ± 1.45	7.09 ± 1.64	0.275
FPG (mmol/l)	7.3 ± 2.7	6.9 ± 2.1	0.164
eGFR (ml/min/1.73m^2)	70.0 (58.94–81.72)	77.8 (57.9–85.0)	0.279
Positive dyslipidemia history (%)	76.5	78.1	0.697
Positive hypertension history (%)	79.3	72.8	0.106
Positive smoking history (%)	45.1	37.1	0.099

Data are presented as mean ± SD, (%). BMI: body mass index; FPG: fasting plasma glucose; CAD: coronary artery disease; T2DM: type 2 diabetes mellitus. Independent -test was used to compare BMI, HbA1c, FPG, and T2DM duration between groups; Mann–Whitney test was used to compare the difference in T2DM duration between two groups. Age was compared by -test. Other phenotypic characteristics were compared by test between groups.