Research Article

Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation

Table 4

Biological parameters in the different groups at the 13th week ().

GroupBW (g)KW/BW (mg/g)FBG (mmol/L)HbA1c (%)SCr (μmol/L)Upro (mg/d)

Control526.9 ± 51.56.1 ± 0.36.95 ± 0.5311.8 ± 0.724.9 ± 2.66.0 ± 1.5
Model452.9 ± 41.18.8 ± 1.532.58 ± 1.3120.3 ± 0.934.8 ± 4.933.8 ± 9.7
LD-ACOS438.7 ± 50.18.5 ± 1.130.96 ± 4.0320.0 ± 1.132.8 ± 4.224.6 ± 8.1#
HD-ACOS466.1 ± 105.37.4 ± 1.1#20.25 ± 7.86##18.4 ± 3.228.9 ± 2.5#18.4 ± 4.6#

and vs. control group; and vs. model group. BW: body weight; KW: kidney weight; FBG: fasting blood glucose; HbA1c: glycosylated hemoglobin A1c; SCr: serum creatinine; Upro: urinary protein.