Clinical Study

Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes

Table 3

Comparison of cognition tests between recently diagnosed type 1 and type 2 diabetes and healthy individuals and between participants with a known type 1 and type 2 diabetes duration of five years after adjusting for crystallized intelligence, age, and sex.

Individuals with recently diagnosed diabetes and metabolically healthy individualsIndividuals with a known diabetes duration of five years
Type 2 diabetes versus type 1 diabetesType 2 diabetes versus healthy individualsType 1 diabetes versus healthy individualsType 2 diabetes versus type 1 diabetes
β (95% CI) valueβ (95% CI) valueβ (95% CI) valueβ (95% CI) value

Verbal memory−0.12 (−0.56; 0.33)0.602−0.49 (−0.93; −0.05)0.029−0.37 (−0.89; 0.14)0.156−0.81 (−1.44; −0.18)0.012
Digit sequencing0.02 (−0.37; 0.41)0.917−0.20 (−0.58; 0.18)0.306−0.22 (−0.67; 0.23)0.3390.34 (−0.22; 0.90)0.227
Token motor task−0.23 (−0.58; 0.13)0.204−0.06 (−0.42; 0.29)0.7160.16 (−0.25; 0.58)0.435−0.21 (−0.79; 0.38)0.486
Verbal fluency−0.03 (−0.43; 0.38)0.897−0.12 (−0.52; 0.28)0.561−0.09 (−0.57; 0.38)0.702−0.24 (−0.76; 0.27)0.347
Symbol coding score0.07 (−0.26; 0.40)0.680−0.12 (−0.45; 0.21)0.483−0.19 (−0.57; 0.20)0.343−0.18 (−0.71; 0.34)0.487
Tower of London−0.08 (−0.39; 0.23)0.6060.03 (−0.28; 0.33)0.8640.11 (−0.25; 0.47)0.557−0.12 (−0.60; 0.36)0.615
BACS composite score−0.08 (−0.42; 0.27)0.659−0.26 (−0.60; 0.08)0.130−0.19 (−0.59; 0.22)0.363−0.32 (−0.83; 0.19)0.221
TMT_A0.52 (−3.42; 4.47)0.794−0.55 (−4.47; 3.36)0.781−1.08 (−5.68; 3.53)0.646−1.75 (−6.83; 3.33)0.495
TMT_B0.81 (−2.63; 4.26)0.642−1.43 (−4.85; 1.99)0.411−2.24 (−6.26; 1.78)0.2730.23 (−4.61; 5.07)0.925
Pictures of facial affect1.72 (−2.15; 5.59)0.3822.00 (−1.85; 5.85)0.3070.28 (−4.25; 4.81)0.9040.17 (−5.20; 5.53)0.096

Data are mean differences (β), 95% confidence intervals (CI), and values from linear regression with MWT-B, as a marker of crystallized intelligence, age, and sex as independent variables and cognition tests as a dependent variable. Italicized print indicates . BACS: Brief Assessment of Cognition in Schizophrenia; TMT_A/B: trail making test A/B.