Association of PD-1 and PD-L1 Genetic Polymorphyisms with Type 1 Diabetes Susceptibility

Table 5

Clinical characteristics of T1DM patients in different genotype of rs4143815.

	PD-L1 rs4143815
	G/G ()	G/C ()	C/C ()	value
Age (years)	25.7 ± 11.6	26.8 ± 13.5	24.5 ± 10.5	0.661
Gender (% males)	46.5	55.3	44.1	0.447
HbA1c (%)	9.0 ± 2.5	8.6 ± 2.8	8.6 ± 2.7	0.737
LDL	2.7 ± 1.2	2.6 ± 0.7	2.6 ± 0.6	0.565
HDL	1.5 ± 0.5	1.6 ± 0.6	1.6 ± 0.4	0.212
Presence of AABs (IAA, ICA, GADA) (%)	72.1	49.4	67.6	0.033^∗

Data are mean—standard deviation (SD); HbA1c: glycated hemoglobin; LDL: low-density lipoprotein; HDL: high-density lipoprotein; AABs: subjects tested for autoantibodies; IAA: insulin autoantibody; ICA: islet cell autoantibody; GADA: glutamic acid decarboxylase autoantibody.