Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 1

Main characteristics of the studies included in this meta-analysis.

References	Study location	Study design	Case group		Control group		MPV measurement trimester	Average age of GDM patients (years)	Average BMI of GDM patients (kg/m^2)	GDM criteria	Quality score
			Sample size	MPV levels	Sample size	MPV levels
Kebapcilar et al., 2016 [12]	Turkey	Case-control	101	9.16 ± 1.04	138	7.42 ± 0.80	Second	26.1	26.9	C&C	8
Sahbaz et al., 2016 [13]	Turkey	Case-control	59	8.93 ± 0.98	60	8.39 ± 1.11	Third	31.4	26.3	C&C	3
Yıldız et al., 2016 [14]	Turkey	Cross-sectional	53	9.98 ± 1.22	35	10.05 ± 1.15	NA	31.5	27.9	C&C	7
Zhu et al., 2015 [15]	China	Case-control	36	10.76 ± 2.02	36	11.07 ± 0.90	Second	31.2	NA	ADA	8
Gorar et al., 2017 [16]	Turkey	Cross-sectional	110	10.4 ± 0.74	159	10.6 ± 0.74	Second	33.0	NA	C&C	4
Yang et al., 2015 [17]	China	Cross-sectional	302	9.0 ± 1.47	310	9.3 ± 1.41	NA	30.6	21.2	ADA	7
Baldane et al., 2015 [21]	Turkey	Cross-sectional	114	10.2 ± 1.05	76	9.9 ± 1.27	Second	29.4	NA	C&C	5
Gur et al., 2015 [22]	Turkey	Cross-sectional	16	10.9 ± 1.0	167	9.6 ± 1.0	Second	29.0	27.1	NDDG	8
Erdogan et al., 2014 [23]	Turkey	Case-control	68	10.5 ± 2.94	61	11.2 ± 1.14	Second	31.8	NA	NDDG	5
Iyidir et al., 2014 [24]	Turkey	Case-control	30	8.8 ± 1.0	38	8.1 ± 0.70	Third	33.7	NA	C&C	8
Maconi et al., 2012 [25]	Italy	Cross-sectional	25	11.9 ± 1.90	100	8.3 ± 1.10	Third	31.4	NA	NA	2
Sak et al., 2012 [26]	Turkey	Case-control	42	8.9 ± 1.90	35	7.8 ± 2.0	Third	31.2	28.6	ADA	6
Erikci et al., 2008 [27]	Turkey	Cross-sectional	34	9.3 ± 1.45	45	8.1 ± 0.66	Third	29.5	NA	ADA	4
Bozkurt et al., 2006 [28]	Turkey	Cross-sectional	100	9.4 ± 1.6	100	8.3 ± 1.1	Third	31	NA	C&C	5
Yin et al., 2005 [29]	China	Cross-sectional	21	9.5 ± 1.6	20	8.7 ± 1.6	Third	27.1	NA	NA	5
Çeltik et al., 2016 [30]	Turkey	Case-control	105	8.66 ± 1.15	40	8.27 ± 0.92	Second	33.4	27.7	ADA	7
Çeltik et al., 2016 [30]	Turkey	Case-control	105	9.59 ± 1.34	40	8.95 ± 1.98	Third	33.4	27.7	ADA
Soydinc et al., 2013 [31]	Turkey	Cross-sectional	42	9.28 ± 0.35	33	7.71 ± 0.19	Third	32.5	28.5	C&C	8
Erdem et al., 2013 [32]	Turkey	Cross-sectional	58	9.43 ± 1.09	219	8.53 ± 0.99	Second	30.1	NA	C&C	6
Köflüfl et al., 2010 [33]	Turkey	Cross-sectional	45	8.67 ± 1.43	239	8.19 ± 0.85	Second	31.2	NA	NDDG	5

MPV: mean platelet volume; GDM: gestational diabetes mellitus; BMI: body mass index; C&C: Carpenter and Coustan; NDDG: National Diabetes Data Group; ADA: American Diabetes Association; NA: not available.